AI Agent and DeSci: The Rise of Emerging Forces

In the past six months, there has been a rising wave of emerging forces in the market concerning AI Agents and DeSci. AI Agents focus on their immense potential in autonomous decision-making, data analysis, and task execution, excelling at solving problems through algorithms; while DeSci is dedicated to breaking traditional barriers in scientific research by utilizing blockchain technology to achieve data sharing and transparency, promoting decentralized knowledge sharing and research funding. This article will summarize and outline the currently prominent and potential tokens related to AI Agents and DeSci.

1. AI Agent's Intelligent AI Carriage

1.1 What is an AI Agent

An AI Agent is an intelligent system that possesses autonomy and goal orientation, capable of perceiving the environment, planning actions, executing tasks, and learning from experience to improve, achieving specific goals without human intervention, such as automatically monitoring data, analyzing anomalies, and making corresponding decisions. In summary, its key characteristics are autonomy and goal orientation.

According to data from the platform, as of December 31, 2024, the current trend of AI is similar to the early signs of the DeFi boom in 2020-2021. The next day, some institutions also proposed ideas regarding AI Agents for 2025: AI agents need independent wallets; decentralized autonomous chatbots; with the widespread use of artificial intelligence, there is a greater need for unique proofs of different AI personalities.

1.2 Popular Token Review

The following is ranked according to the dynamic Mindshare consumer mindset share:

• AIXBT

Market Cap: $550 million, Mind Share: 20.7%

AIXBT tracks hot discussions on encrypted social media and utilizes its proprietary engine to identify strong narratives and games. Token holders can access its analytics platform.

• Virtuals

Market Cap: $4 billion, Mind Share: 20.7%

Virtuals has designed an Initial Asset Offering (IAO) model, allowing users to generate new AI agents by locking $VIRTUAL, and the created tokens will automatically pair with the locked $VIRTUAL to form a liquidity pool. According to a data panel's statistics on January 1, nearly 13,000 AI Agents based on Virtuals have been launched.

• AI16Z

Market Cap: $2 billion, Mind Share: 8.57%

The project architecture and the relationships between various entities are as follows: ai16z is a permissionless DAO, possessing the tokens ai16z and degenai; ElizaOS is an open-source AI agent framework; Eliza Labs is responsible for developing elizaOS; the ELIZA token is developed by an independent team, receiving team support but is not an official product.

• Fartcoin

Market Cap: $900 million, Mind Share: 6.93%

Fartcoin is located in a certain public chain ecosystem and is a meme coin conceptualized by Terminal of Truth ( CTO ). It allows users to submit fart jokes and memes in exchange for tokens, tokenizing farts with the help of sentient robots.

• Zerebro

Market Cap: $560 million, Mind Share: 4.36%

The Zerebro project is a self-operating AI agent focused on artistic creation and content generation, capable of independently creating music, memes, artworks, and NFTs, and interacting and operating across multiple platforms.

• Griffain

Market Cap: $380 million, Mind Share: 3.53%

Griffain is a new AI Agent built on a certain blockchain. Its design aims to simplify user interactions with cryptocurrencies by integrating personal and professional AI agents. Griffain can automatically perform complex tasks such as wallet management, token trading, and NFT minting.

• SNAI

Market Cap: $83 million, Mind Share: 1.95%

SNAI is the token behind the cloud server protocol SwarmNode.ai (SNAI) proxy platform.

• GOAT

Market Cap: $560 million, Mind Share: 1.91%

Gospel of Goatse is a meme coin released from a certain platform, fine-tuned by an artificial intelligence platform and trained based on social media data.

• ARC

Market Cap: $300 million, Mind Share: 1.89%

ARC is an AI conceptual token, and its team is related to the AI development framework of "rig", representing the concept of AI infrastructure.

• TRISIG

Market cap: $74 million, Mind share: 1.47%

TriSig is a clever crypto analyst who claims to be able to identify early alpha projects and answers challenging questions in a simplified manner, sharing his views on any significant events or trends in the cryptocurrency market.

• ALCH

Market Cap: $150 million, Mind Share: 1.38%

Alchemist AI is a no-code application generation platform that allows users to quickly generate different applications and products using natural language descriptions and leveraging public AI capabilities. Unlike traditional AI agents, Alchemist AI does not require users to create different AI agents, but instead automates application generation through the AI capabilities provided by the platform.

• Spore.fun

Market Cap: $62 million, Mind Share: 1.3%

It is the first experimental autonomous reproductive AI evolution platform that combines the Eliza Framework, a certain public chain's pump.fun, and TEE verifiable computing to create an ecosystem where AI agents can not only survive but also reproduce and adapt autonomously, completely free from human intervention.

• VADER

Market Cap: $110 million, Mind Share: 1.13%

VaderAI aims to become an AI agent investment DAO manager, capable of participating in DAOs with virtual agents and applying to set up its own DAO.

• Luna

Market Cap: $140 million, Mind Share 0.97%

Luna has her own wallet on a certain public chain, through which she can independently receive tokens and send rewards to her fans; this robot has already released songs on a streaming platform.

• Bully

Market Cap: 72 million, Mind Share: 0.7%

The core of BULLY is Dolos the Bully, a token representing a witty and straightforward AI character. This character draws inspiration from Greek mythology, interacting with users through sharp humor and bold commentary.

1.3 Views on AI Agents

The current craze surrounding AI Agents is reflected in on-chain data, similar to the situation before the DeFi boom in 2020-2021. However, Blockchain+AI at this stage still struggles to create the momentum for an AI Summer. From the perspective of on-chain analysis, certain public chains have become the main battlegrounds, with high performance and high speculation becoming the key carriers for AI Agents. Currently, the classification of AI projects is visibly rising rapidly, with noteworthy directions including computing power, infrastructure, Meme, launch platforms, applications, and more.

Compared to market hype, the application of AI Agent in actual data analysis is more valuable. Taking the example of Trump coming to power at the beginning of 2024 (January 20), by analyzing on-chain and market data, we can analyze whether there are other reasons, aside from winning the election, for Trump's change in attitude towards cryptocurrency, including collaborations and demands with other consortiums, to predict his future commitment to cryptocurrency.

The logic of AI itself requires data and guidance on right and wrong, while blockchain has the natural advantage of data transparency on-chain. Therefore, from a trend perspective, blockchain is the best breeding ground for the development of AI. The on-chain opportunities for AI Agents represent a trend outlook of a Fomo-guided approach combined with value investment. However, it is undeniable that the market speculation around AI Agent tokens has also shown us the hope for the real application of Blockchain + AI in the future. The current market speculation expectations mainly focus on the following five points:

1. The hype and continuous price manipulation of certain projects drive FOMO sentiment throughout the entire AI Agent market;

2. The self-initiated iterative evolution of AI Agents shifts the project's progression from manual to automated.

3. Similar to the social media analysis of certain projects that assesses market trends, it offers investors alternative perspectives and viewpoints. Judging from the quality of the content sent and the market recognition, it is not inferior to KOL standards.

4. Some projects launched last year achieved great success by adopting strategies similar to those of other platforms.

5. AI virtual humans and AI creations have opened up new mature markets in the non-cryptocurrency field. Today's spiritual leaders and image ambassadors are not necessarily equivalent to humans; they can also be equivalent to "AI image products." The narrative of blockchain + AI will have greater breakthrough effects.

2. The Life Science Carriage of DeSci

2.1 What is DeSci

If AI Agents are an inevitable product of technological iteration, then DeSci is a byproduct of recent hot events. DeSci (Decentralized Science) is a model that constructs a fair and equitable scientific research infrastructure through Web3 technology, aimed at addressing issues in scientific research such as peer review, funding, intellectual property management, and data transparency and review mechanisms. It attempts to bring the speculative nature of the cryptocurrency space into the non-speculative realm of scientific research.

Although DeSci entered the public eye as early as 2021 with the establishment of VitaDAO, it has not received widespread attention until recently when a trading platform invested in and launched BIO Protocol, and some well-known industry figures participated in an offline conference themed on DeSci in Bangkok, which brought this sector back into the market's focus.

2.2 BioDAO Protocol

BIO Protocol is a decentralized science (DeSci) curation and liquidity protocol, initially invested in by a certain institution, aimed at providing resource support for scientific research projects and promoting innovation in research.

The core components of the protocol include BioDAO, a curation system, intellectual property tokenization and liquidity mechanisms, as well as incentive systems. Through multiple rounds of auctions and airdrop programs, the BIO Protocol has built a diverse and highly participatory community, laying the foundation for a decentralized biomedical research network.

Funds are primarily raised through token sales to support the development of biotechnology projects and to create shared intellectual property ownership among members. According to official information, BioDAO: Launch has successfully launched 7 sub-DAOs, with another 3 sub-DAOs currently in development.

The 7 launched sub-DAOs include:

• VITA (VitaDAO): Focused on early longevity science research, it has received investment from a well-known pharmaceutical company. Co-founder Paul Kohlhaas is the initiator and author of the white paper for VitaDAO.

• ATH ( AthenaDAO ): Focused on research and drug development in women's reproductive health;

• GROW (ValleyDAO): A decentralized community governance platform focused on anti-aging drugs and longevity projects;

• PSY (PsyDAO): Focused on psychedelic science research, the first round of token sales was completed in November 2024, raising $2 million;

• HAIR (HairDAO): Dedicated to solving hair loss issues, has launched Follicool shampoo, priced at $49.95 per bottle, and buyers will receive 1 million POO tokens;

• CRYO (CryoDAO): Promoting research in the field of cryopreservation;

• NEURON (CerebrumDAO): Dedicated to brain health research, has raised over $1.5 million.

The 3 sub-DAOs that are under development include:

• Long Covid Labs: Focused on research of long-term sequelae of COVID-19;

• QuantumBioDAO: Dedicated to research in quantum biology;

• Curetopia: Focused on research of genetic diseases.

2.3 PumpScience

The DeSci platform Molecule DAO of a certain public chain ecosystem is a token launch platform introduced at a certain conference. Pump.science will issue tokens representing pharmaceuticals on Pump.fun, and the related concept tokens include:

RIF: Rifampicin (, "Rifampicin is an antibiotic that has garnered attention for its remarkable effects on aging. In microorganisms such as Caenorhabditis elegans (a model organism frequently used in aging research), rifampicin has been shown to activate the cell's natural defense mechanisms to resist stress and damage. Imagine it as a 'cell coach' that encourages cells to stay healthy and resilient by protecting them from harmful oxidative stress and maintaining the quality of intracellular proteins. These protective effects help the worms live longer and healthier."

URO: Urolithin A, "This is a compound that your body produces when you consume foods rich in ellagitannins, such as pomegranates. The unique aspect of Urolithin A is its ability to perform a 'spring cleaning' for your cells. It helps to clear out old, dysfunctional mitochondria (the energy factories of cells), allowing fresh, healthy mitochondria to thrive. This process is known as mitophagy, and research indicates that it can extend